Michael J. Econs


Distinguished Professor (2019)
Distinguished Professor
Indiana University Purdue University Indianapolis (IUPUI)
School of Medicine
Titled Professor (2007)
Glenn W. Irwin, Jr. Professor of Endocrinology and Metabolism
Indiana University Purdue University Indianapolis (IUPUI)
School of Medicine
Department of Medicine


Michael J. Econs is a leading geneticist in metabolic bone diseases whose research focuses on rare and poorly understood disorders, such as X-linked hypophosphatemic rickets and autosomal dominant hypophosphatemic rickets. His research has played a critical role in the discovery of the genes responsible for both of these disorders.

Econs' work has led to new diagnostic and therapeutic tools, including the recent approval by the European Union and the FDA of Burosumab, the first treatment for X-linked hypophosphatemic rickets in 30 years. The treatment has already had an impact on patients' lives, restoring height in children, healing fractures and giving them the likelihood of avoiding many orthopedic surgeries. His discoveries represent the first time in the history of the IU School of Medicine that a faculty member has driven the science from concept through an FDA-approved therapy.