Sophie Paczesny


Titled Professor (2017)
Nora Letzter Professor
Indiana University Purdue University Indianapolis (IUPUI)
School of Medicine
Department of Pediatrics


Dr. Paczesny's areas of interest are: Pediatric hematology/oncology, particularly in HSCT, with a focus on translational research science and with the goal of converting bench discoveries to the bedside.

An Associate Professor of the Blood Marrow and Stem Cell Transplant Program at the Indiana University School of Medicine, Dr. Paczesny leads the Blood and Marrow Transplantation Program acute graft-versus-host disease (GVHD) biomarker discovery and validation research. She received her MD and PhD from Paris University, France, where she completed her residency and fellowship in Pediatric Hematology/Oncology and Bone Marrow Transplantation. She joined first the Blood and Marrow Transplantation Program at the University of Michigan in 2006 where she has developed proteomics for the diagnosis of GVHD, a complication that occurs in approximately half of patients following allogeneic hematopoietic cell transplantation. With her responsibilities at Indiana University and affiliations with the Simon Cancer Center, Wells Center for Pediatric Research, Department of Pediatrics, and Department of Immunology, Paczesny is pursuing her research of discovery and validation of biomarkers of complications post-transplantation as well as bring new targeted therapies to the clinic and explore novel pathways in GVHD.